Scientific Research
on Blue Light

"Our underlying theory is that the reduction in blue-light exposure is the likely mechanism whereby amber lenses, compared to clear lenses, improve sleep in individuals with insomnia symptoms."

“We conclude that the use of [blue light-blocking] glasses in male adolescents while sitting in front of an LED screen in the evening can attenuate melatonin suppression and alerting effects before sleep. BB glasses therefore have the potential to acutely impede the negative effects modern lighting imposes on circadian physiology in the evening.

"Our results show that, according to some sleep indices, sleep quality is significantly better in healthy adults after using the blue-light shield eyewear while using self-luminous portable devices at night."

"Blue blockers represent an elegant means to prevent the light-induced melatonin suppression."

“Our data show that, irrespective of gender, orange lens glasses can effectively block the capacity, of a 1-hr light pulse of 1300 lx in the eye, to suppress melatonin production.”

"The amber lens group experienced significant improvement in sleep quality relative to the control group."

"Subjects completing the study showed subjectively reduced anxiety and improved sleep quality on multiple measures."

"Both the orange-tinted glasses and the “sleep-aware” app significantly reduced short-wavelength emissions."

"Blue-blockers seem to improve daytime sleep of permanent night-shift workers."

"All new mothers may benefit from using glasses and light bulbs that block blue light when getting up at night to care for their babies."

"Use of amber lenses to produce evening ‘‘virtual darkness’’ should produce a circadian phase advance."

"Blue Blocker glasses are effective and feasible as add-on treatment for bipolar mania."

"Implantation of blue light-filtering IOLs which mimic the natural human lens should be considered as a safe and relatively inexpensive preventive measure to reduce the potential risk for retinal phototoxicity and its associated potential risk for AMD in pseudophakic eyes."

"Polychromatic action spectra were reasonably consistent in indicating that the spectral region between 400nm and 550nm provides the strongest. stimulation of circadian and neuroendocrine responses."This means is the wavelengths of light between 400 - 550nm should be completely blocked for optimal melatonin secretion after dark.

"ocular light exposure influences many aspects of human physiology and behaviour, including circadian rhythms, sleep, and alertness (both via circadian system–dependent and circadian system–independent routes), mood, neuroendocrine, and cognitive functions."

"Given the widespread use of electronic devices today, our findings suggest that screen light exposure at evening may have detrimental effects on human health and performance."

"Exposure to Artificial Light At Night (ALAN) results in a disruption of the circadian system, which is deleterious to health." 

"The IARC has classified shift work in group 2A of “probable carcinogens to humans” since “they involve a circadian disorganization.”

"Shorter wavelength light exposure increases ongoing nonvisual cognitive activity in subcortical and cortical brain areas."

"Entrainment is a fundamental property of circadian systems by which the period of the internal clock is synchronized to the period of the entraining stimuli. An important aspect of entrainment in humans is the maintenance of an appropriate phase relationship between the circadian system, the timing of sleep and wakefulness, and environmental time (a.k.a. the phase angle of entrainment) to maintain wakefulness throughout the day and consolidated sleep at night."

"Exposure to light can have both positive and negative impacts on human health."

"Artificial light at night (ALAN) is mentioned as disturbing sleep."

"We demonstrate that a few tens of seconds of light induce immediate and significant wavelength dependent changes in brain activity."

“Some people consider the progress in the field of light and health over the last couple of years as the most important light induced innovation since the invention of the light bulb” 

"A new study of preschoolers finds that exposure to even very low intensities of light before bedtime can sharply reduce production of the sleep-promoting hormone melatonin, interfering with sleep. It suggests that young children are highly susceptible to the physiological impacts of light at night and some kids are more sensitive than others."

"short-wave blue light with wavelength between 415 nm and 455 nm is closely related to eye light damage. This high energy blue light passes through the cornea and lens to the retina causing diseases such as dry eye, cataract, age-related macular degeneration"

"harmful blue light-induced effects on human eyes should not be ignored, blue light can also produce different degree of damage to corneal, crystal lens and retina. Therefore, it is necessary to take appropriate protective measures when using blue light-related products"

"The blue component of LED is the major cause of retinal damage"

"LED light caused a state of suffering of the retina with oxidative damage and retinal injury. We observed a loss of photoreceptors and the activation of caspase-independent apoptosis, necroptosis, and necrosis"

"Retinal photodamage caused by a conventional light source (cold) can become chronic if exposure is high and long enough. In contrast, the use of blue-blocking filters can significantly alleviate the functional loss of retinal photosensitive cells. Therefore, these filters might be an effective mechanism to protect us from ocular pathologies"

"Overexposure to blue light with short wavelengths can induce oxidative damage and apoptosis to the cornea, which may manifest as increased ocular surface inflammation and resultant dry eye."

"blue LED light has been shown to induce more damage than white or green light, and induce ROS production and lipid peroxidation in RPE cells, resulting in apoptotic cell death. Finally, intense blue light can cause mitochondrial and nuclear DNA damage."

"It is seen that with LED sources the severity and range of flicker is relatively very high when compared to conventional lights."

"The various adverse effects of flicker include eye strain, fatigue, headache, migraine, blurred vision as well as photo epilepsy in sensitive individuals"

"The purpose of the study was to compare the impact on subjective well-being, performance and physiological arousal of fluorescent light powered by conventional and high-frequency ballasts."

"Flickering light has been shown to have detrimental effects in humans and other species."

"It is clear that centrally mediated circadian rhythms play an important role in human health."

"Blue light damage is not an uncommon feature of the skin and eye."